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Invitrogen™ Isatuximab Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA559214
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Beschreibung
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
Isatuximab is an IgG1 chimeric monoclonal antibody that targets a specific epitope of plasma cell CD38 receptor and can trigger a variety of unique mechanisms of action, including the promotion of programmed tumor cell death (apoptosis) and immunomodulatory activity. CD38 is expressed at high levels on MM cells and is a cell surface receptor target for antibody therapy in MM and other malignant tumors.
Spezifikation
| Isatuximab Humanized | |
| Recombinant Monoclonal | |
| Unconjugated | |
| hu38SB19; SAR-650984 | |
| Protein A | |
| RUO | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance | |
| 1 mg/mL | |
| 25mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2 | |
| Human | |
| 1 mg | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
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