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Isonipecotamid, 98 %, Thermo Scientific Chemicals

Product Code. 11495493
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Product Code. 11495493 Supplier Thermo Scientific Alfa Aesar Supplier No. A13442.18
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Description

CAS: 39546-32-2 | C6H12N2O | 128.18 g/mol

Isonipecotamide is used as a reactant for the preparation of Survival motor neuron (SMN) protein modulators, orally available naphthyridine protein kinase D inhibitors and heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase. It is also used to prepare phosphodiesterase 5 inhibitors. It is also used as a reactant for identification of small molecular inhibitors of importin-beta mediated nuclear import. It is also used as a fluorenylmethyloxycarbonyl - deprotection agent in organic synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Anwendungen
Isonipecotamid wird als Reaktant für die Herstellung von Survival-Motor-Neuron(SMN)-Proteinmodulatoren, oral verfügbaren Naphthyridin-Protein-Kinase-D-Inhibitoren und heteroalicyclischen Carboxamidinen als Inhibitoren der induzierbaren Stickstoffmonoxid-Synthase verwendet. Es wird auch zur Herstellung von Phosphodiesterase-5-Inhibitoren verwendet. Es wird auch als Reaktant zur Identifizierung kleiner molekularer Inhibitoren des Importin-beta-vermitteltem Kernimports verwendet. Es wird auch als Fluorenylmethyloxycarbonyl-Entschützungsmittel in der organischen Synthese verwendet.

Löslichkeit
Wasserlöslich.

Hinweise
Feuchtigkeitsempfindlich. Hygroskopisch. Nicht kompatibel mit starken Oxidationsmitteln.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 39546-32-2
Summenformel C6H12N2O
Molekulargewicht (g/mol) 128.18
MDL-Nummer MFCD00038012
InChI-Schlüssel DPBWFNDFMCCGGJ-UHFFFAOYSA-N
Synonym isonipecotamide, 4-piperidinecarboxamide, hexahydroisonicotinamide, 4-carbamoylpiperidine, isonipectoamide, piperidine-4-carboxylic acid amide, 4-piperdinecarboxamide, piperidin-4-carboxamid, iso nipecotamide, iso-nipecotamide
PubChem CID 3772
IUPAC-Name Piperidin-4-Carboxamid
SMILES NC(=O)C1CCNCC1

Specifications

Chemischer Name oder Material Isonipecotamide
Schmelzpunkt 148°C to 149°C
Menge 50 g
Beilstein 112554
Empfindlichkeit Hygroskopisch
Löslichkeitsinformationen Soluble in water.
Formelmasse 128.18
Reinheit (%) 98%

RUO – Research Use Only

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