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Invitrogen™ KIM-1 Recombinant Rabbit Monoclonal Antibody (309)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA560561
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Beschreibung
KIM-1 Recombinant Monoclonal Antibody for ELISA
CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein that consists of extracellular N-terminal immunoglobulin V-like domain and a mucin domain, and a short cytoplasmic tail. The endogenous ligand for CD365 is Tim-4. In addition, CD365 is known to be a cellular receptor or co-receptor for a number of viruses including hepatitis A and C viruses, Ebola virus, Marburg virus, Dengue virus, Zika virus, West Nile virus, and Japanese encephalitis virus. The direct binding of the viruses by CD365 occurs via phosphatildyl-serine exposed on viral envelopes. Polymorphisms within human CD365 gene (HAVCR1) are associated with susceptibility to infection and the disease severity. CD365 has also been implicated in the T cell co-stimulation. CD365 is primarily expressed in epithelial cells. It is also highly expressed in A549, 769-P and Caco-2 and cell lines. CD365 exists also as a soluble protein generated by metalloproteinase mediated proteolytic cleavage of the surface protein.
Spezifikation
| KIM-1 | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 612069 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA | |
| 309 | |
| Unconjugated | |
| Havcr1 | |
| Havcr1 | |
| Recombinant Canine TIM-1/KIM-1/HACVR protein (Tyr21-Ser160). | |
| 20 μL | |
| Primary | |
| Canine | |
| Antibody | |
| IgG |
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