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  6. Microphthalmia (Transcription Factor) (MiTF) Ab-2 Mouse Monoclonal Antibody, Epredia™

Microphthalmia (Transcription Factor) (MiTF) Ab-2 Mouse Monoclonal Antibody, Epredia™

Artikelnummer. 12652307 Alle ansehen Epredia Produkte
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Menge:
100 μL
200 μL
500 μL
1 mL
7 mL
Konjugat:
Unconjugated
Form:
Concentrated
Prediluted
Konzentration:
1mg/mL
200μg/mL
Packungsgröße:
1 Milliliter
100 Mikroliter
200 Mikroliter
500 Mikroliter
7 Milliliter
Artikelnummer. Menge Konjugat Form Konzentration unitSize
12652307 100 μL Unconjugated Concentrated 200μg/mL 100 Mikroliter
12672307 100 μL Unconjugated Concentrated 1mg/mL 100 Mikroliter
12682307 200 μL Unconjugated Concentrated 1mg/mL 200 Mikroliter
12662307 500 μL Unconjugated Concentrated 200μg/mL 500 Mikroliter
12642307 1 mL Unconjugated Concentrated 200μg/mL 1 Milliliter
12612317 7 mL Unconjugated Prediluted - 7 Milliliter
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Código de producto. 12652307

Marca: Epredia MS772P0

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Descripción

Ensure accurate, reproducible results in immunohistochemistry experiments with the Epredia™ Microphthalmia (Transcription Factor) (MiTF) Ab-2, Mouse Monoclonal Antibody.

Mi is a basic helix-loop-helix-leucine zipper (b-HLH-ZIP) transcription factor implicated in pigmentation, mast cells and bone development. The mutation of Mi causes Waardenburg Syndrome type II in humans. In mice, a profound loss of pigmented cells in the skin eye and inner ear results, as well as osteopetrosis and defects in natural killer and mast cells. There are two known isoforms of Mi differing by 66 amino acids at the NH2 terminus. Shorter forms are expressed in melanocytes and run as two bands at 52kDa and 56kDa, while the longer Mi form runs as a cluster of bands at 60-70kDa in osteoclasts and in B16 melonoma cells (but not other melanoma cell lines), as well as mast cells and heart.

Host Species: Mouse

Clone: D5

Isotype: IgG1/κ

Species Reactivity: Human and Dog. Does not react with mouse and rat. Others not known.

Epitope: N-terminal

Immunogen: N-terminal fragment of human Mi protein

Molecular Weight: 52-56kDa doublet

Positive Control: 501 Mel cells, Melanoma

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not verified)
  • Gel Supershift

Note:

USA: RUO; Int'l: RUO

TRUSTED_SUSTAINABILITY

Especificaciones

Antigen Microphthalmia (Transcription Factor) (MiTF) Ab-2
Anwendungen Immunohistochemistry (Paraffin)
Klassifikation Monoclonal
Klon D5
Konzentration 200μg/mL
Konjugat Unconjugated
Wirtsspezies Mouse
Immunogen N-terminal fragment of human Mi protein
Menge 100 μL
Regulatorischer Status RUO
Forschungsgebiet Transcription Regulation
Primär oder sekundär Primary
Zielspezies Canine, Human
Form Concentrated
Isotype IgG2a κ
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