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p53 Ab-6 Mouse Monoclonal Antibody, Epredia™
Achieve accurate, reproducible results with the Epredia™ p53 Ab-6, Mouse Monoclonal Antibody.
Marke: Epredia MS-187-PABX
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Beschreibung
p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.Host Species: Mouse
Clone: DO-1
Isotype: IgG2a
Species Reactivity: Human, Monkey and Cow. Reacts weakly with Mouse and Rat. Others not known.
Epitope: aa 11-25
Immunogen: Recombinant human wild-type p53 protein expressed in E. coli
Molecular Weight: 53kDa
Positive Control: SKBR-3 cells or MDA-231 cells, Colon CA
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunofluorescence
- Immunoprecipitation (Native and denatured)
- Flow Cytometry
- Gel Supershift Assay
Note:
USA: RUO; Int'l: RUO
Spezifikation
| p53 Ab-6 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 200 μL | |
| Cell Cycle | |
| Bovine, Human, Non-human Primate | |
| IgG2a |
| Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| DO-1 | |
| Unconjugated | |
| Recombinant human wild-type p53 protein expressed in E. coli | |
| RUO | |
| Primary | |
| Concentrated |
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