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Descripción
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. The acidic keratins have molecular weights of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40 kDa. The basic keratins have molecular weights of 65-67, 64, 59, 58, 56 and 52 kDa. Members of acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with cell type, differentiation status and environment. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Host Species: Mouse
Clone: AE1/AE3
Isotype: IgG1 + IgG1
Species Reactivity: Human, Monkey, Cow, Rabbit, Mouse, Rat and Chicken. Others not known.
Immunogen: Human epidermal keratin
Positive Control: Skin, Lung CA
Cellular Localization: Cytoplasmic
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Immunofluorescence
Especificaciones
Especificaciones
| Antigen | Cytokeratin, Pan Ab-1 |
| Anwendungen | Immunofluorescence, Immunohistochemistry (Paraffin) |
| Klassifikation | Monoclonal |
| Klon | AE1/AE3 |
| Konzentration | Prediluted |
| Konjugat | Unconjugated |
| Wirtsspezies | Mouse |
| Immunogen | Human epidermal keratin |
| Menge | 12 mL |
| Regulatorischer Status | IVD |
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Título del producto
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