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Tubulin-α Ab-2 Mouse Monoclonal Antibody, Epredia™

Artikelnummer. 12624269 Alle ansehen Epredia Produkte
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Menge:
100 μL
200 μL
500 μL
1 mL
7 mL
Form:
Concentrated
Prediluted
Konzentration:
1mg/mL
200μg/mL
Prediluted
Packungsgröße:
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100 Mikroliter
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Artikelnummer. Menge Form Konzentration unitSize
12624269 500 μL Concentrated 200μg/mL 500 Mikroliter
12641667 100 μL Concentrated 200μg/mL 100 Mikroliter
12661667 100 μL Concentrated 1mg/mL 100 Mikroliter
12671667 200 μL Concentrated 1mg/mL -
12631667 1 mL Concentrated 200μg/mL 1 Milliliter
12601677 7 mL Prediluted Prediluted -
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Artikelnummer. 12624269

Marke: Epredia MS581P1

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Beschreibung

Provide accurate, reproducible results with the Epredia™ Tubulin-α Ab-2, Mouse Monoclonal Antibody.

Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55kDa subunits: α and Β. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton.

Host Species: Mouse

Clone: DM1A

Isotype: IgG1/κ

Species Reactivity: Human, Cow, Pig, Rat, Mouse, Guinea Pig, Gerbil, Frog and Chicken. Others not known.

Epitope: aa 426-450

Immunogen: Native chick brain microtubules

Molecular Weight: 57kDa

Positive Control: Ls174T, MAD109 cells; skin or lung

Cellular Localization: Cytoplasmic Ab-2 causes the 10nm filaments to collapse into large lateral aggregates collecting in the cell periphery or tight juxtanuclear caps. It does not block microtubule assembly. It does not inhibit polymerization or depolymerization of platelet tubulin in vitro. It blocks (by 70-80%) the ability of tubulin dimers (with GppNHp bound) to promote a stable inhibition of adenylyl cyclase.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

TRUSTED_SUSTAINABILITY

Specifications

Antigen Tubulin, alpha Ab-2
Anwendungen Immunoassay, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Klassifikation Monoclonal
Klon DM1A
Konzentration 200μg/mL
Konjugat Unconjugated
Wirtsspezies Mouse
Immunogen Native chick brain microtubules
Menge 500 μL
Regulatorischer Status RUO
Forschungsgebiet Cytoskeletal Protein
Primär oder sekundär Primary
Zielspezies Bovine, Chicken, Frog, Gerbil, Guinea Pig, Human, Mouse, Pig, Rat
Form Concentrated
Isotype IgG2a κ
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