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Tubulin-α Ab-2 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ Tubulin-α Ab-2, Mouse Monoclonal Antibody.
Marke: Epredia MS-581-P
Weitere Details : Netto-Gewicht : 4.98950kg
Beschreibung
Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55kDa subunits: α and Β. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton.Host Species: Mouse
Clone: DM1A
Isotype: IgG1/κ
Species Reactivity: Human, Cow, Pig, Rat, Mouse, Guinea Pig, Gerbil, Frog and Chicken. Others not known.
Epitope: aa 426-450
Immunogen: Native chick brain microtubules
Molecular Weight: 57kDa
Positive Control: Ls174T, MAD109 cells; skin or lung
Cellular Localization: Cytoplasmic Ab-2 causes the 10nm filaments to collapse into large lateral aggregates collecting in the cell periphery or tight juxtanuclear caps. It does not block microtubule assembly. It does not inhibit polymerization or depolymerization of platelet tubulin in vitro. It blocks (by 70-80%) the ability of tubulin dimers (with GppNHp bound) to promote a stable inhibition of adenylyl cyclase.
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunofluorescence
- Immunoprecipitation (Native and denatured)
- Electron Microscopy
Note:
USA: RUO; Int'l: RUO
Spezifikation
| Tubulin, alpha Ab-2 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 1 mL | |
| Cytoskeletal Protein | |
| Bovine, Chicken, Frog, Gerbil, Guinea Pig, Human, Mouse, Porcine, Rat | |
| IgG2a κ |
| Immunoassay, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| DM1A | |
| Unconjugated | |
| Native chick brain microtubules | |
| RUO | |
| Primary | |
| Concentrated |