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Invitrogen™ LXR beta Polyclonal Antibody
Rabbit Polyclonal Antibody
Marke: Invitrogen™ PA529771
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Beschreibung
Recommended positive controls: HeLa, mouse brain. Predicted reactivity: Mouse (93%), Rat (92%), Rabbit (93%), Rhesus Monkey (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The liver X receptors, LXRA and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.
Spezifikation
| LXR beta | |
| Polyclonal | |
| Unconjugated | |
| NR1H2 | |
| AI194859; liver X nuclear receptor beta; liver X receptor beta; LX receptor beta; LXR; LXR beta; LXRB; LXR-b; LXRbeta; NER; NER1; NER-I; Nr1h2; NR1H2 protein; nuclear orphan receptor LXR-beta; nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; nuclear receptor subfamily 1, group H, member 2; OR-1; Orphan nuclear receptor OR-1; oxysterols receptor LXR-beta; Retinoid X receptor-interacting protein No.15; RIP15; steroid hormone-nuclear receptor NER; ubiquitous receptor; ubiquitously-expressed nuclear receptor; ubiquitously-expressed nuclear receptor 2; UNR; Unr2; UR | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 22260, 7376 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 | |
| P55055, Q60644 | |
| NR1H2 | |
| Recombinant protein encompassing a sequence within the center region of human LXR beta. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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