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Invitrogen™ MKL1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marke: Invitrogen™ PA5109961
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Beschreibung
Immunogen sequence: MPPLKSPAAF HEQRRSLERA RTEDYLKRKI RSRPERSELV RMHILEETSA EPSLQAKQLK LKRARLADDL NEKIAQRPGP MELVEKNILP VESSLKEAII VGQVNYPKVA DSSSFDEDSS DALSPEQPAS HESQGSVPSP LEARVSEPLL SATSASPTQV VSQLPMGRDS REMLFLAEQP PLPPPPLLPP SLTNGTTIPT AKSTPTLIKQ SQPKSASEKS QRSKKAKELK PKVKKLKYHQ YIPPDQKQDR GAPPMDSSYA KILQQQQLFL QLQILNQQQQ.
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia.
Spezifikation
| MKL1 | |
| Polyclonal | |
| Unconjugated | |
| Mrtfa | |
| AMKL; basic SAP and coiled-coil domains; basic SAP coiled-coil transcription activator; basic, SAP and coiled-coil domain; basic, SAP, and coiled-coil domain containing protein; Bsac; FLMKL1; KIAA1438; Mal; megakaryoblastic leukemia (translocation) 1; megakaryoblastic leukemia (translocation) 1 homolog; megakaryoblastic leukemia 1 met; megakaryoblastic leukemia 1 protein; Megakaryoblastic leukemia 1 protein homolog; Megakaryocytic acute leukemia protein; Megakaryocytic acute leukemia protein homolog; MELODY; mixed lineage leukemia; MKL (megakaryoblastic leukemia)/myocardin-like 1; MKL/myocardin-like protein 1; MKL1; MKL1-elongated derivative of yield protein; MKL1met; MRTFA; MRTF-A; myocardin related transcription factor A; myocardin-related transcription factor A | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 223701, 315151, 57591 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot, Immunocytochemistry | |
| 0.85 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q8K4J6, Q969V6 | |
| Mrtfa | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human MKL1 (NP_065882.1). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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