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Gibco™ Mouse FGF-4 Recombinant Protein, PeproTech®

Artikelnummer. 17804573
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Menge:
100 μg
2 x 500 μg
25 μg
250 μg
5 μg
500 μg
Pakningsstørrelse:
1 Milligramm
100 Mikrogramm
2 Stück
25 Mikrogramm
250 Mikrogramm
5 Mikrogramm
500 Mikrogramm
Artikelnummer. Menge unitSize
17804573 2 x 500 μg 1 Milligramm
17834363 100 μg 100 Mikrogramm
30087730 2 x 500 μg 2 Stück
17853933 250 μg 250 Mikrogramm
17843853 25 μg 25 Mikrogramm
17804793 500 μg 500 Mikrogramm
17873853 5 μg 5 Mikrogramm
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Artikelnummer. 17804573

Brand: Gibco™ 450571MG

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Beskrivelse

Recombinant Protein

450-57-1MG will be provided as 2 x 500 μg (450-57-500UG). Recombinant Murine FGF-4 is a 19.0 kDa protein consisting of 173 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
TRUSTED_SUSTAINABILITY

Tekniske data

Zugriffsnummer P11403
Zur Verwendung mit (Anwendung) Functional Assay
Zusammensetzung protein with no preservative
Gen-ID (Entrez) 14175
Molekulargewicht 19
Name Mouse FGF-4
Menge 2 x 500 μg
Quelle E. coli
Lagerungsbedingungen -20°C
Kennzeichnung RUO
Endotoxin-Konzentration <1 EU/μg
Gen-Alias FGF; FGF4; Fgf-4; Fgfk; Fibroblast growth factor; fibroblast growth factor 4; fibroblast growth factor 4 splice isoform; HBGF-4; heparin secretory transforming protein 1; heparin secretory-transforming protein 1; heparin-binding growth factor 1; heparin-binding growth factor 4; HST; Hst1; hst-1; HSTF1; HSTF-1; human stomach cancer, transforming factor from FGF-related oncogene; kaposi sarcoma oncogene; Kfgf; K-FGF; K-fibroblast growth factor; KS3; oncogene HST; transforming protein KS3
Gensymbol Fgf4
Spezifische Reaktivität Mouse
Konjugat Unconjugated
Rekombinant Recombinant
Sequenz APNGTRHAEL GHGWDGLVAR SLARLPVAAQ PPQAAVRSGA GDYLLGLKRL RRLYCNVGIG FHLQVLPDGR IGGVHADTRD SLLELSPVQR GVVSIFGVAS RFFVAMSSRG KLFGVPFFTD ECKFKEILLP NNYNAYESYA YPGMFMALSK NGRTKKGNRV SPTMKVTHFL PRL
Form Lyophilized
Reinheits- oder Qualitätsgrad ≥ 95% by SDS-PAGE gel and HPLC analyses.
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