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Invitrogen™ MYT1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marke: Invitrogen™ PA588052
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Beschreibung
Immunogen sequence: KPQDLPSKSV DIEVDENGTL DLSMHKHRKR ENAFPSSSSC SSSPGVKSPD ASQRHSSTSA PSSSMTSPQS SQASRQDEWD RPLDYTKPSR LREEEPEESE PAAHSFASSE ADDQEVSEEN FEERKYPGEV TLTNFKLKFL SKDIKKELLT CPTPGCDGSG HITGNYASHR S; Positive Samples: U-87MG, U-251MG, Mouse liver, Mouse kidney, Rat kidney, Rat liver; Cellular Location: Nucleus.
The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.
Spezifikation
| MYT1 | |
| Polyclonal | |
| Unconjugated | |
| MYT1 | |
| C20orf36; KIAA0835; KIAA1050; MTF1; myelin transcription factor 1; Myelin transcription factor I; MYT1; MyTI; Neural zinc finger factor 2; neural zinc finger transcription factor 2; Nzf2; NZF-2; Nzf2a; Nzf2b; Nztf2; PLPB1; proteolipid protein binding protein; proteolipid protein-binding protein; ZC2H2C1; ZC2HC4A | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 17932, 362291, 4661 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 1.68 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| Q01538, Q8CFC2 | |
| MYT1 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 650-820 of human MYT1 (NP_0045261). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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