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Nifedipine, 98%

Artikelnummer. 15495109
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Artikelnummer. 15495109 Lieferant Thermo Scientific Alfa Aesar Lieferanten-Nr. J62811.06
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Beschreibung

L-type calcium channel blocker; induces apoptosis in human glioblastoma cells | CAS: 21829-25-4 | C17H18N2O6 | 346.34 g/mol

L-type calcium channel blocker; induces apoptosis in human glioblastoma cells.Nifedipine is a dihydropyridine calcium channel blocker used as L-type calcium channel blocker, antianginal and an antihypertensive . It induces apoptosis in human glioblastoma cells. It is used as a coronary vasodilator in the treatment of cardiac and circulatory disorders. Further, it is used in high-altitude medicine to treat high altitude pulmonary edema, hypertension and chronic stable angina. In addition, it is frequently used as a tocolytic agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
L-type calcium channel blocker; induces apoptosis in human glioblastoma cells.Nifedipine is a dihydropyridine calcium channel blocker used as L-type calcium channel blocker, antianginal and an antihypertensive . It induces apoptosis in human glioblastoma cells. It is used as a coronary vasodilator in the treatment of cardiac and circulatory disorders. Further, it is used in high-altitude medicine to treat high altitude pulmonary edema, hypertension and chronic stable angina. In addition, it is frequently used as a tocolytic agent.

Solubility
Soluble in acetone, methylene chloride, chloroform, ethyl acetate, dimethyl sulfoxide and methanol. Sparingly soluble in ethanol. Insoluble in water.

Notes
Light sensitive. Store in a cool place. Incompatible with strong acids, strong oxidizing agents, caustics, aliphatic amines, amides, diethylamine, potassium hydride and potassium hydroxide.
TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 21829-25-4
Summenformel C17H18N2O6
Molekulargewicht (g/mol) 346.34
MDL-Nummer MFCD00057326
InChI-Schlüssel HYIMSNHJOBLJNT-UHFFFAOYSA-N
Synonym nifedipine, procardia, adalat, procardia xl, adalat cc, cordipin, corinfar, fenihidine, citilat, oxcord
PubChem CID 4485
ChEBI CHEBI:7565
IUPAC-Name 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
SMILES COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC

Specifications

Chemischer Name oder Material Nifedipine
Schmelzpunkt 171°C to 175°C
Farbe Weiß bis gelb
Menge 5 g
Merck Index 14,6528
Löslichkeitsinformationen Soluble in acetone,methylene chloride,chloroform,ethyl acetate,dimethyl sulfoxide and methanol. Sparingly soluble in ethanol. Insoluble in water.
Formelmasse 346.33
Reinheit (%) 98%
Physikalische Form Pulver

Safety and Handling

compliance-icons
Product Identifier
  • Nifedipine
 Signal Word
  • Achtung
 Hazard Category
  • Akute Toxizität Kategorie 4
 Hazard Statement
  • H302-Gesundheitsschädlich bei Verschlucken.
 Precautionary Statement
  • P301+P312-BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/ Arzt anrufen /
Supplemental information
  • MIXTURE LIST-Contain: Nifedipine
SDS

RUO – Research Use Only

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