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Invitrogen™ Nurr1 Polyclonal Antibody

Artikelnummer. 10607990
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Menge:
400 μL
Packungsgröße:
100 Mikrogramm
Artikelnummer. Menge unitSize
10607990 400 μL 100 Mikrogramm
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Artikelnummer. 10607990

Marke: Invitrogen™ PA513416

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Beschreibung

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine and rat based on sequence homology.

The Nuclear receptor related 1 protein (Nurr1) also known as NR4A2 (nuclear receptor subfamily 4, group A, member 2) is a protein that in humans is encoded by the NR4A2 gene. NURR1 is a member of the nuclear receptor family of intracellular transcription factors.Nurr1 plays a key role in the maintenance of the dopaminergic system of the brain. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's disease, schizophrenia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full-length nature has not been determined.
TRUSTED_SUSTAINABILITY

Spezifikation

Antigen Nurr1
Anwendungen Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Klassifikation Polyclonal
Konzentration 1.8 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with 0.09% sodium azide; pH 7.4
Gen NR4A2
Gen-Zugriffsnummer P43354, Q06219
Gen-Alias HZF3; Hzf-3; Immediate-early response protein NOT; intermediate-early receptor protein; NGFI-B; NGFI-B beta; NGFI-B/nur77 beta-type transcription factor homolog; NOT; NR4A2; Nuclear orphan receptor HZF-3; nuclear receptor related 1; nuclear receptor subfamily 4 group A member 2; nuclear receptor subfamily 4 group A member 2 variant TINUR; nuclear receptor subfamily 4 group A member 2 variant NURR1a; nuclear receptor subfamily 4 group A member 2 variant NURR1b; nuclear receptor subfamily 4 group A member 2 variant NURR1c; nuclear receptor subfamily 4 group A member 2 variant NURR2c; nuclear receptor subfamily 4, group A, member 2; nur related protein 1; nur related protein-1, human homolog of; Nurr1; NUR-related factor 1; orphan nuclear receptor NR4A2; orphan nuclear receptor NURR1; Regenerating liver nuclear receptor 1; RNR1; RNR-1; SL-322; T-cell nuclear receptor NOT; TINOR; TINUR; transcriptionally inducible nuclear receptor related 1; transcriptionally-inducible nuclear receptor
Gensymbole NR4A2
Wirtsspezies Rabbit
Immunogen KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human NURR1 (NR4A2).
Reinigungsverfahren Ammonium sulfate precipitation, Size-exclusion - Dialysis
Menge 400 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 18227, 4929
Zielspezies Human, Mouse
Inhalt und Lagerung Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotype IgG
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