Ion Torrent™ Oncomine™ Comprehensive Assay Plus GX

Key features of the assay include:

• Enables CGP across 517 genes
• Accurately detects SNVs, indels, CNVs, including large genomic rearrangements (LGRs) in BRCA1 and BRCA2, and fusions including splice variants
• Assesses for genomic signatures, including HRD, TMB, and MSI, to help maximize insights on the underlying oncogenic drivers
• Provides robust performance from 30 ng of DNA and/or 20 ng of RNA isolated from FFPE samples, including fine needle biopsies
• Provides multiplex sequencing of up to four DNA samples (DNA + RNA or DNA-only) with optional NTC on a GX7 Chip in a single run
• Provides multiplex sequencing of up to eight RNA-only samples (or eight plus optional NTC) per GX7
• System-installed assays preconfigured with settings optimized for specific applications and sample types
• Requires as little as 10 minutes hands-on time per run for easy, automated workflows
• Provides automated Nucleic Acid to Result workflow on the Genexus Integrated Sequencer with next-day results

When used with the Genexus Purification System and the Genexus Integrated Sequencer, sequential sample purification, library preparation, sequencing, and analysis allow for the reporting of next-day results. With just two user touchpoints and as little as 20 minutes of hands-on time, the easy, automated workflows can help reduce handling errors, free up time for your laboratory staff, and reduce labor costs. As a single vendor of sample-to-report solutions, including instruments, consumables, analysis, and support, Thermo Fisher Scientific simplifies bringing in-house CGP to your lab at varying levels of NGS expertise.