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Invitrogen™ OTUB1 Monoclonal Antibody (24GB6500)
Beschreibung
OTUB1 Monoclonal Antibody for Western Blot
The product of this gene is a member of the OTU superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
Spezifikation
Spezifikation
| Antigen | OTUB1 |
| Anwendungen | Flow Cytometry, Western Blot, Immunocytochemistry |
| Klassifikation | Monoclonal |
| Klon | 24GB6500 |
| Konjugat | Unconjugated |
| Zusammensetzung | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gen | OTUB1 |
| Gen-Zugriffsnummer | Q96FW1 |
| Gen-Alias | AI850305; Deubiquitinating enzyme OTUB1; deubiquitinating enzyme OTUB1 {ECO:0000250; EMBL:AAI66771.1}; FLJ20113; FLJ40710; hOTU1; HSPC263; hypothetical protein LOC540984; MGC111158; MGC4584; OTB1; OTU deubiquitinase, ubiquitin aldehyde binding 1; OTU domain, ubiquitin aldehyde binding 1; OTU domain-containing ubiquitin aldehyde-binding protein 1; OTU domain-containing ubiquitin aldehyde-binding protein 1 {ECO:0000250; OTU1; OTUB1; otub1 {ECO:0000312; otubain 1; otubain-1; otubain-1 {ECO:0000250; OTU-domain Ubal-binding 1; Ubiquitin thioesterase OTUB1; ubiquitin thioesterase OTUB1 {ECO:0000250; ubiquitin-specific protease otubain 1; ubiquitin-specific-processing protease OTUB1; ubiquitin-specific-processing protease OTUB1 {ECO:0000250; UniProtKB:Q7TQI3} |
| Gensymbole | OTUB1 |
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