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PAX8 Rabbit anti-Human, CoraLite 488, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech CL488-10336-100UL

Weitere Details : Netto-Gewicht : 0.00010kg

Artikelnummer. 17204666

  • 367.00 € / 100 Mikroliter
Verfügbar ab: 24-06-2024
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Beschreibung

Beschreibung

PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. It is expressed during organogenesis of the thyroid gland, kidney and Mullerian system. It is thought to regulate the expression of Wilms tumor suppressor (WT1) gene and mutations in PAX8 have been associated with Wilms tumor cells, thyroid and ovarian carcinomas. PAX8 is a useful marker in distinguishing ovarian carcinomas from mammary carcinomas (PMID: 18724243). PAX8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. This antibody can detect all 5 isoforms of PAX8 (31 kDa, 34 kDa, 41 kDa, 43 kDa and 48 kDa). A 58-60 kDa form has also been reported (PMID:15650356, 1049952). Proteintech's 10336-1-AP antibody has cross-reactivities with the other PAX family members.

Spezifikation

Spezifikation

PAX8
Polyclonal
CoraLite 488
100 μL
7849
Liquid
Immunofluorescence
1000 μg/mL
Rabbit
Primary
Human
IgG
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote