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Invitrogen™ PD-L1 Recombinant Rabbit Monoclonal Antibody (611), PE
Beschreibung
PD-L1 Recombinant Monoclonal Antibody for Flow
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
Spezifikation
Spezifikation
| Antigen | PD-L1 |
| Anwendungen | Flow Cytometry |
| Klassifikation | Recombinant Monoclonal |
| Klon | 611 |
| Konzentration | 0.1 mg/mL |
| Konjugat | PE |
| Zusammensetzung | PBS with 0.5% BSA and 0.03% ProClin 300 |
| Gen | Cd274 |
| Gen-Zugriffsnummer | Q9NZQ7 |
| Gen-Alias | A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1 |
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