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  6. Invitrogen™ Phospho-Chk2 (Thr68) Recombinant Rabbit Monoclonal Antibody (Chk2T68-D12), APC, Invitrogen™

Invitrogen™ Phospho-Chk2 (Thr68) Recombinant Rabbit Monoclonal Antibody (Chk2T68-D12), APC, Invitrogen™
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Rabbit Recombinant Monoclonal Antibody

202.00 € - 506.00 €

Specifica

Antigen Phospho-Chk2 (Thr68)
Klon Chk2T68-D12
Anwendungen Flow Cytometry
Klassifikation Recombinant Monoclonal
Konjugat APC
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Prodotti 2
Codice del prodotto Marca Menge Prezzo Quantità e disponibilità  
Codice del prodotto Marca Menge Prezzo Quantità e disponibilità  
17166858
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Invitrogen™
MA537270 		10 Tests
202.00 €
10 Stück
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17146578
GREENER_CHOICE
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Invitrogen™
MA536988 		100 Tests
506.00 €
100 Stück
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Descrizione

Descrizione

CHEK2 (CHK2) is a serine/threonine kinase and a component of the DNA damage checkpoint pathway. A mutation in CHK2 has been linked to cancer. CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins. In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage. Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53. Also, mutations in CHK2 are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.
Specifica

Specifica

Phospho-Chk2 (Thr68)
Flow Cytometry
APC
Rabbit
Human, Mouse
O96017, Q9Z265
11200, 50883
A synthetic phosphor-peptide corresponding to residues surrounding to Thr68 of human phospho Chk2.
Primary
4°C
Chek2
Chk2T68-D12
Recombinant Monoclonal
Liquid
RUO
PBS with 0.20% BSA and 0.09% sodium azide
CDS1; cds1 homolog; Checkpoint kinase 2; Checkpoint like protein CHK2; checkpoint-like protein CHK2; Chek2; Chk2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; CHK2 checkpoint homolog (S. pombe); Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; HuCds 1; HuCds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; Rad53; Rad53 homolog; RP11-436C9.1; Serine/threonine protein kinase Chk2; serine/threonine-protein kinase Chk2
Chek2
IgG κ
Protein A/G
Antibody
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