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Invitrogen™ Phospho-LAT (Tyr220) Recombinant Rabbit Monoclonal Antibody (24GB1375)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA557160
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Beschreibung
Phospho-LAT (Tyr220) Recombinant Monoclonal Antibody for Western Blot
LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. After immunoreceptor triggering, LAT becomes multiply tyrosine-phosphorylated by Syk-, Src-, or Tec-family kinases, providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FcepsilonRI-dependent mast cell activation, as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.
Spezifikation
| Phospho-LAT (Tyr220) | |
| Recombinant Monoclonal | |
| 2.35 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O43561, O54957, O70601 | |
| LAT | |
| A synthesized peptide derived from human Phospho-LAT (Tyr220) (aa 213-227). | |
| 20 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Western Blot, Immunocytochemistry | |
| 24GB1375 | |
| Unconjugated | |
| LAT | |
| 36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; Lat; LAT1; linker for activation of T cells; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells; linker for activation of T-cells family member 1; linker protein; p36-38; pp36 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 16797, 27040, 81511 | |
| -20°C | |
| Liquid |
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