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Invitrogen™ Phospho-RAD17 (Ser656) Recombinant Rabbit Monoclonal Antibody (24GB795)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA557600
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Beschreibung
Phospho-RAD17 (Ser656) Recombinant Monoclonal Antibody for Western Blot, Flow
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
Spezifikation
| Phospho-RAD17 (Ser656) | |
| Recombinant Monoclonal | |
| Unconjugated | |
| Rad17 | |
| CCYC; cell cycle checkpoint protein (RAD17); cell cycle checkpoint protein RAD17; DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; hRad17; MmRad24; R24L; RAD1 homolog; RAD17; RAD17 (Ser647); RAD17 checkpoint clamp loader component; RAD17 homolog; RAD17 homolog (S. pombe); Rad17 like protein; Rad17-like protein; Rad17p; RAD17SP; RAD24; RF-C activator 1 homolog; RF-C/activator 1 homolog; YOR368W | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 19356, 5884 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 24GB795 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O75943, Q6NXW6 | |
| Rad17 | |
| A synthesized peptide derived from human Phospho-Rad17 (Ser656) (aa 649-663). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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