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Invitrogen™ PLD2 Polyclonal Antibody
Goat Polyclonal Antibody
Marke: Invitrogen™ PA5148466
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Beschreibung
Reconstitute at 0.2 mg/mL in sterile PBS.
PLD2 is a peripheral membrane protein belonging to phospholipase D family with a PH domain, two PLD phosphodiesterase domains and a PX (phox homology) domain that plays a regulatory rather than catalytic role. PLD2 catalyzes the hydrolysis of phosphatidylcholine (PC) to produce phosphatidic acid and choline. PLD2 may function in regulated secretion, signal-induced cytoskeletal regulation and/or endocytosis, transcriptional regulation, and cell cycle control. It is usually stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and activated by the ADP-ribosylation factor-1 (ARF-1). PLD2 is activated by agonist stimulation of both tyrosine kinase and G protein-coupled receptors and is also known to interact with EGFR and PIP5K1A. PLD2, localized to plasma membrane caveolae, is ubiquitously expressed in most tissues.
Spezifikation
| PLD2 | |
| Polyclonal | |
| Unconjugated | |
| Pld2 | |
| choline phosphatase 2; hPLD2; phosphatidylcholine-hydrolyzing phospholipase D2; phospholipase D gene 2; phospholipase D2; PLD 2; PLD1C; PLD2; Pldc; rPLD2 | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 5338 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| O14939 | |
| Pld2 | |
| E. coli-derived recombinant human PLD2, Met1-His117. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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