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Invitrogen™ POLB Recombinant Rabbit Monoclonal Antibody (24GB1475)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA557384
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Beschreibung
POLB Recombinant Monoclonal Antibody for Western Blot
DNA polymerase beta comprises an amino-terminal 8- kDa domain and a carboxy-terminal 31- kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase beta, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates beta-pol level. DNA polymerase beta fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells.
Spezifikation
| POLB | |
| Recombinant Monoclonal | |
| Unconjugated | |
| POLB | |
| A430088C08Rik; DNA pol beta; DNA polymerase beta; DNA polymerase beta subunit; DNA-directed DNA polymerase beta; hypothetical protein LOC614688; LOW QUALITY PROTEIN: DNA polymerase beta; MGC125976; POL B; Pol beta; POLB; polb.S; polymerase (DNA directed), beta; polymerase (DNA directed), beta S homeolog; polymerase (DNA) beta; polymerase B; polymerase-beta; wu:fa97a05; XELAEV_18020165mg; zgc:109924 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 18970, 29240, 5423 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 24GB1475 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P06746, P06766, Q8K409 | |
| POLB | |
| A synthesized peptide derived from human DNA polymerase beta (aa 300-335). | |
| 20 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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