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Invitrogen™ POLI Recombinant Rabbit Monoclonal Antibody (HL3115)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA556680
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Descrizione
POLI Recombinant Monoclonal Antibody for Western Blot
Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity.
Specifica
| POLI | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| Q6R3M4, Q9UNA4 | |
| Poli | |
| Recombinant fragment of human DNA polymerase iota. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| Western Blot | |
| HL3115 | |
| Unconjugated | |
| Poli | |
| DNA polymerase iota; eta2; Poli; polymerase (DNA directed) iota; polymerase (DNA directed), iota; polymerase (DNA) iota; polymerase (DNA-directed), iota; RAD 30B; RAD30; RAD30 homolog B; RAD30B; RAD3OB | |
| Rabbit | |
| Protein A | |
| RUO | |
| 11201, 26447 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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