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Invitrogen™ PTP1B Polyclonal Antibody
Goat Polyclonal Antibody
Marke: Invitrogen™ PA5148488
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Beschreibung
Reconstitute at 0.2 mg/mL in sterile PBS.
PTP1B (PTPN1) is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK and in turn inactivates the protein kinase activity of EIF2AK3/PERK. PTP1B also plays a role in CKII- and p60c-src-induced signal transduction cascades. It regulates the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. PTP1B also regulates the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
Spezifikation
| PTP1B | |
| Polyclonal | |
| Unconjugated | |
| PTPN1 | |
| CPTP1; EC 3.1.3.48; EGK_02300; hgnc9642; KIAA0283; protein tyrosine phosphatase 1B; protein tyrosine phosphatase non-receptor type 1; protein tyrosine phosphatase, non-receptor type 1; protein tyrosine phosphatase, placental; protein-protein-tyrosine phosphatase HA2; protein-tyrosine phosphatase 1B; Protein-tyrosine phosphatase HA2; PTN1; Ptp; PTP1B; PTP-1B; ptp1b protein; PTP-HA2; Ptpn1; RP5-1121H13.2; RPTPrho; tyrosine phosphatase 1b; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 1; wu:fk54h03 | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 19246, 24697, 5770 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| P18031, P20417, P35821 | |
| PTPN1 | |
| E. coli-derived recombinant human PTP1B, Glu2-Asn321. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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