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Invitrogen™ Rad52 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marke: Invitrogen™ PA5102689
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Beschreibung
Antibody detects endogenous levels of total RAD52.
DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. Double-strand breaks are generally thought to be repaired via one of two distinct mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ). Homologous recombination requires the activity of the members of the RAD52 epistasis group, which includeRAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2. RAD52 can catalyze strand annealing reactions, and can form oligomers that attach to ends of single-stranded DNA.
Spezifikation
| Rad52 | |
| Polyclonal | |
| Unconjugated | |
| RAD52 | |
| DNA repair protein RAD52 homolog; RAD52; RAD52 homolog (S. cerevisiae); RAD52 homolog, DNA repair protein; Rad52yh; recombination protein RAD52; rhabdomyosarcoma antigen MU-RMS-40.23 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 19365, 297561, 5893 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P43351, P43352 | |
| RAD52 | |
| A synthesized peptide derived from human RAD52(Accession P43351), corresponding to amino acid residues G80-E130. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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