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Tocris Bioscience™ Rapamycin

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Menge:
1 mg
Packungsgröße:
1 Milligramm
Beschreibung
Rapamycin is a antifungal and immunosuppressant. Specific inhibitor of mTOR (mammalian target of Rapamycin). Complexes with FKBP-12 and binds mTOR inhibiting its activity. Inhibits interleukin-2-induced phosphorylation and activation of p70 S6 kinase. Induces autophagy in yeast and mammalian cell lines. Drives hPSC differentiation to mesendoderm and blood progenitor cells. Also used as a chemical dimerizer; rapamycin and GA3-AM (Cat. No. 5407) chemically inducible dimerization systems are orthogonal. Inhibits MERS-CoV infection of Huh7 cells in a plaque reduction assay. Enhances lentiviral transduction of hematopoietic stem cells.
Spezifikation
Spezifikation
| Chemischer Name oder Material | Rapamycin |
| CAS | 53123-88-9 |
| Menge | 1 mg |
| Summenformel | C51H79NO13 |
| Formelmasse | 914.18 |
| Produkttyp | Rapamycin |
| Reinheit | 98% |
| Molekulargewicht | 914.187 |
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