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Invitrogen™ RAR gamma-1 Recombinant Rabbit Monoclonal Antibody (PSH07-19)
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Product Code. 30484990
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Menge:
100 μL
Unit Size:
100 Mikroliter
Product Code. Menge unitSize
30484990 100 μL 100 Mikroliter
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Product Code. 30484990

Brand: Invitrogen™ MA560185

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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: SK-Br-3 cell lysate, T-47D cell lysate, A375 cell lysate, HeLa cell lysate, MEF cell lysate, Mouse skin tissue lysate, Rat skin tissue lysate, human skin tissue, mouse skin tissue, rat skin tissue. Tissue Specificity: Tissue enhanced (esophagus, skin). Subcellular Location: Nucleus, Cytoplasm. Sequence Similarities: 100% Mouse/Rat. Predicted band size: 50 kDa.

Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma. Two main isoforms of RAR gamma exist: RAR gamma-1 has been found to be predominantly expressed in skin, while RAR gamma-2 has been found early in embryogenesis and in embryonal carcinoma cells. RAR gamma is also known as RARD. The corresponding gene for the retinoic acid receptor gamma 1 is NR1B3.
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Specifications

Antigen RAR gamma-1
Anwendungen Immunohistochemistry (Paraffin), Western Blot
Klassifikation Recombinant Monoclonal
Klon PSH07-19
Konzentration 1 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gen Rarg
Gen-Zugriffsnummer P13631, P18911
Gen-Alias Nr1b3; Nuclear receptor subfamily 1 group B member 3; RAR gamma 2; RAR Gamma-1; RARC; RARD; Rarg; RAR-gamma; RARgamma2; retinoic acid; retinoic acid nuclear receptor gamma variant 1; retinoic acid nuclear receptor gamma variant 2; retinoic acid receptor; retinoic acid receptor gamma; retinoic acid receptor gamma 4; retinoic acid receptor, gamma
Gensymbole Rarg
Wirtsspezies Rabbit
Immunogen Recombinant protein within human RARG aa 155-454.
Reinigungsverfahren Protein A
Menge 100 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 19411, 5916, 685072
Zielspezies Human, Mouse, Rat
Inhalt und Lagerung Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotype IgG
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