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Invitrogen™ Reelin Monoclonal Antibody (397919)
Rat Monoclonal Antibody
Marke: Invitrogen™ MA561347
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Beschreibung
Reconstitute at 0.5 mg/mL in sterile PBS.
Reelin in an extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
Spezifikation
| Reelin | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q60841 | |
| RELN | |
| Mouse myeloma cell line NS0-derived recombinant mouse Reelin, Ala27-Met862. | |
| 100 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a |
| Western Blot | |
| 397919 | |
| Unconjugated | |
| RELN | |
| ETL7; extracellular matrix serine protease; LIS2; PRO1598; Reelen; reeler; Reeler protein; Reelin; RELN; Rl | |
| Rat | |
| Protein A/G | |
| RUO | |
| 19699 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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