Invitrogen™ REG1A/REG1B Polyclonal Antibody

Beschreibung

Reconstitute with sterile PBS to a final concentration of 0.2 mg/mL.

REG1A (Regenerating Islet-Derived 1 Alpha) and REG1B (Regenerating Islet-Derived 1 Beta) are genes that encode proteins belonging to the regenerating gene (REG) family, which are involved in tissue regeneration, cell proliferation, and differentiation. These proteins are predominantly expressed in the pancreas and play a significant role in the regeneration of pancreatic islet cells, which are crucial for insulin production. REG1A and REG1B are also involved in the maintenance and repair of the gastrointestinal tract lining. Elevated levels of REG proteins have been observed in conditions such as diabetes, pancreatitis, and certain gastrointestinal diseases, indicating their importance in disease pathology and potential as biomarkers. Additionally, these proteins may have roles in tumorigenesis, as their expression is often upregulated in various cancers, including pancreatic and colorectal cancers. Understanding the regulation and function of REG1A and REG1B is essential for developing therapeutic strategies aimed at enhancing tissue regeneration and treating related diseases. Their involvement in cell growth and repair processes makes them promising targets for research in regenerative medicine and oncology.