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Invitrogen™ RFC1 Recombinant Rabbit Monoclonal Antibody (HL3242)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA556860
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Beschreibung
RFC1 Recombinant Monoclonal Antibody for Western Blot, ICC/IF
Replication factor C (RFC) is an essential DNA polymerase accessory protein that is required for numerous aspects of DNA metabolism, including DNA replication, DNA repair and telomere metabolism. RFC is a heteropentameric complex that recognizes a primer on a template DNA, binds to a primer terminus and loads proliferating cell nuclear antigen (PCNA) onto DNA at primer-template junctions in an ATP-dependent reaction. All five of the RFC subunits share a set of related sequences (RFC boxes) that include nucleotide binding consensus sequences. Four of the five RFC genes (RFC1, RFC2, RFC3 and RFC4) have consensus ATP-binding motifs. The small RFC proteins, RFC2, RFC3, RFC4 and RFC5, interact with Rad24, whereas the RFC1 subunit does not. RFC2, the third-largest subunit of the RFC complex, exhibits ATP binding which makes it important for both DNA replication and checkpoint function.
Spezifikation
| RFC1 | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| P35251, P35601 | |
| RFC1 | |
| Recombinant fragment of human RFC1. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| Western Blot, Immunocytochemistry | |
| HL3242 | |
| Unconjugated | |
| RFC1 | |
| 140kDa; A1; A1 140 kDa subunit; A1-P145; Activator 1 140 kDa subunit; activator 1 large subunit; Activator 1 subunit 1; Alp145; Differentiation-specific element-binding protein; DNA-binding protein PO-GA; Ibf-1; ISRE-binding protein; MHC binding factor, beta; MHCBFB; PO-GA; RECC1; replication factor C (activator 1) 1; replication factor C (activator 1) 1, 145kDa; replication factor C 1; replication factor C 140 kDa subunit; Replication factor C large subunit; replication factor C subunit 1; Replication factor C subunit 1-like protein; replication factor C, 140 kDa; replication factor C1; RFC; RF-C 140 kDa subunit; Rfc1; RFC140 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 19687, 5981 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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