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Invitrogen™ RFC1 Recombinant Rabbit Monoclonal Antibody (HL3242)

Rabbit Recombinant Monoclonal Antibody

Marke:  Invitrogen™ MA556860

Artikelnummer. 30275326

  • 500.00 € / 100 Mikroliter

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Beschreibung

Beschreibung

RFC1 Recombinant Monoclonal Antibody for Western Blot, ICC/IF

Replication factor C (RFC) is an essential DNA polymerase accessory protein that is required for numerous aspects of DNA metabolism, including DNA replication, DNA repair and telomere metabolism. RFC is a heteropentameric complex that recognizes a primer on a template DNA, binds to a primer terminus and loads proliferating cell nuclear antigen (PCNA) onto DNA at primer-template junctions in an ATP-dependent reaction. All five of the RFC subunits share a set of related sequences (RFC boxes) that include nucleotide binding consensus sequences. Four of the five RFC genes (RFC1, RFC2, RFC3 and RFC4) have consensus ATP-binding motifs. The small RFC proteins, RFC2, RFC3, RFC4 and RFC5, interact with Rad24, whereas the RFC1 subunit does not. RFC2, the third-largest subunit of the RFC complex, exhibits ATP binding which makes it important for both DNA replication and checkpoint function.
TRUSTED_SUSTAINABILITY
Spezifikation

Spezifikation

RFC1
Recombinant Monoclonal
1 mg/mL
PBS with no preservative
P35251, P35601
RFC1
Recombinant fragment of human RFC1.
100 μL
Primary
Human, Mouse
Antibody
IgG
Western Blot, Immunocytochemistry
HL3242
Unconjugated
RFC1
140kDa; A1; A1 140 kDa subunit; A1-P145; Activator 1 140 kDa subunit; activator 1 large subunit; Activator 1 subunit 1; Alp145; Differentiation-specific element-binding protein; DNA-binding protein PO-GA; Ibf-1; ISRE-binding protein; MHC binding factor, beta; MHCBFB; PO-GA; RECC1; replication factor C (activator 1) 1; replication factor C (activator 1) 1, 145kDa; replication factor C 1; replication factor C 140 kDa subunit; Replication factor C large subunit; replication factor C subunit 1; Replication factor C subunit 1-like protein; replication factor C, 140 kDa; replication factor C1; RFC; RF-C 140 kDa subunit; Rfc1; RFC140
Rabbit
Protein A
RUO
19687, 5981
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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