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Invitrogen™ RhoGAP Polyclonal Antibody
Sheep Polyclonal Antibody
Marke: Invitrogen™ PA5149199
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Beschreibung
Reconstitute at 0.2 mg/mL in sterile PBS.
The p190 RhoGAP protein is associated with p120 RasGAP in growth-factor stimulated and tyrosine kinase transformed cells. It functions as a GTPase - activating protein (GAP) for Rho and Rac family proteins, which are involved in regulating cytoskeletal actin and membrane ruffling. The antibody appears to couple signal transduction via Ras and Rho through its association with RasGAP. The presence of two adjacent SH2 domains in the p21 RAS GAP indicates that GAP might interact directly with tyrosine kinases.
Spezifikation
| RhoGAP | |
| Polyclonal | |
| Unconjugated | |
| ARHGAP1 | |
| ARHGAP1; ARHGAP5; B230365D05Rik; C76222; CDC42 GTPase-activating protein; CDC42GAP; GFI2; growth factor independent 2; GTPase-activating protein rhoGAP; GTPase-activating protein rhoOGAP; GTPase-activating protein, Rho, 1; LOC512817 protein; p100 RasGAP-associated p105 protein; p105 RhoGAP; p190-B; p190BRhoGAP; p50rhoGAP; p50-RhoGAP; Rho GTPase activating protein 1; Rho GTPase activating protein 5; rho GTPase-activating protein 1; Rho GTPase-activating protein 5; RHOGAP; RHOGAP1; RHOGAP5; rho-related small GTPase protein activator; Rho-type GTPase-activating protein 1; rho-type GTPase-activating protein 5 | |
| Sheep | |
| Antigen affinity chromatography | |
| RUO | |
| 228359, 311193, 392 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| Q07960, Q5FWK3 | |
| ARHGAP1 | |
| E. coli-derived recombinant human ARHGAP1, aa 1-62. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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