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Invitrogen™ RIP3 Recombinant Rabbit Monoclonal Antibody (PSH04-79)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA556484
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Beschreibung
RIP3 Recombinant Monoclonal Antibody for Western Blot, IHC (P)
RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, which contains a C-terminal domain unique from other RIP family members. RIPK3 is predominantly localized to the cytoplasm, and specifically, are colocalized in the mitochondrion which can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. RIPK3 is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor and caspase-8 prevents RIPK3-dependent necrosis without inducing apoptosis by functioning in a proteolytically active complex with CFLAR and that this complex is required for the protective function.
Spezifikation
| RIP3 | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 | |
| Q9Y572 | |
| RIPK3 | |
| Synthetic peptide within human RIP3 aa 469-518/518. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Immunohistochemistry (Paraffin), Western Blot | |
| PSH04-79 | |
| Unconjugated | |
| RIPK3 | |
| 2610528K09Rik; AW107945; Hcyp2; Homocysteine respondent protein HCYP2; mRIP3; receptor interacting protein 3; receptor interacting serine/threonine kinase 3; receptor-interacting protein 3; receptor-interacting serine/threonine-protein kinase 3; receptor-interacting serine-threonine kinase 3; Rip3; RIP-3; Ripk3; RIP-like protein kinase 3 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 11035 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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