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Invitrogen™ Sambucus Nigra (Elderberry Bark) Lectin (SNA, EBL), fluorescein (FITC)

Artikelnummer. 16872070
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Menge:
2 mg
Packungsgröße:
2 Milligramm
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16872070 2 mg 2 Milligramm
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Artikelnummer. 16872070 Lieferant Invitrogen™ Lieferanten-Nr. L32479

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Beschreibung

Bright-green SNA-fluorophor conjugate

  • Sambucus Nigra (Elderberry Bark) Lectin (SNA, EBL), fluorescein (FITC), is a bright-green SNA-fluorophor conjugate. SNA belongs to the group of type 2 ribosome-inactivating proteins and is composed of an A-chain with enzymatic activity and a B-chain with carbohydrate-binding activity. SNA can induce apoptosis through the caspase-dependent pathway at low concentrations.
  • This effect depends on the carbohydrate binding of the B-chain and is independent from the catalytic activity of the A-chain. In colon cancers, it has been reported that 90% of carcinomas express increased levels of sialic acid, linked to galactose residues on the surface of tumor cells, that is detectable with SNA.
  • Very bright FITC conjugate detected with traditional FITC/GFP filter set, Ex/Em: 495/515 nm
  • Applications: immunofluorescence, glycobiology
  • Sugar specificity: sialic acid
  • Inhibiting/eluting sugar: 500 mM lactose
  • Blood group specificity: non-specific, A > B, O
  • Unconjugated lectin molecular weight: 140 KDa
  • Immunofluorescence working concentration: 5–20 μg/mL
  • SNA-FITC is provided at a 2 mg/mL concentration in 10 mM HEPES, 0.15 M NaCl, pH 7.5, 0.08% sodium azide. 0.1 mM Ca2+
  • A precipitate may form during storage. This does not have a significant adverse effect on the product. If a precipitate forms upon long-term storage at 4°C, warm to 37°C and centrifuge before use.
TRUSTED_SUSTAINABILITY

Spezifikation

Menge 2 mg
Quelle Elderberry
Konjugat Fluorescein
Inhalt und Lagerung When stored at or below 2°C to 8°C in the dark, the product is stable for 6 months after reciept.
Markertyp Classic Dyes
Versandbedingung Approved for shipment at Room Temperature or on Wet Ice
Form Solution
Protein-Subtyp Lectins

For Research Use Only. Not for use in diagnostic procedures.

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