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  6. Invitrogen™ SARS-CoV-2 Alpha Spike Protein RBD Chimeric Recombinant Human Monoclonal Antibody (D004)

Invitrogen™ SARS-CoV-2 Alpha Spike Protein RBD Chimeric Recombinant Human Monoclonal Antibody (D004)
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Artikelnummer. 30535066
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20 Mikrogramm
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30534989 20 μg 20 Mikrogramm
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Artikelnummer. 30535066 Lieferant Invitrogen™ Lieferanten-Nr. MA560602

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Beschreibung

Human Recombinant Monoclonal Antibody

Specifically recognize the SARS-CoV-2 Alpha Spike RBD and ECD. No cross-reactivity with SARS-CoV-2, Beta, Delta, Omicron BA.4/BA.5/BA.5.2, Omicron BA.2.75 variant. Has Medium cross-reactivity in ELISA with SARS-CoV-2 wild type Spike RBD.. Has cross-reactivity in ELISA with: SARS-CoV-2 Alpha (B.1.1.7) Spike S1+S2 trimer Protein; SARS-CoV-2 Alpha (B.1.1.7) Spike RBD Protein; Has Medium cross-reactivity in ELISA with: SARS-CoV-2 Spike RBD Protein; No cross-reactivity in ELISA with: SARS-CoV-2 Omicron (XBB.1.16) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB.1.5) Spike RBD Protein; SARS-CoV-2 Omicron (XBB.1.5) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB.1) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB) Spike RBD Protein; SARS-CoV-2 Omicron (BQ.1.1) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BQ.1.1) Spike RBD Protein; SARS-CoV-2 Omicron (BF.7) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4.6/BF.7) Spike RBD Protein; SARS-CoV-2 Omicron (BA.4.6) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4/BA.5/BA.5.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4/BA.5/BA.5.2) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2.75) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2.75) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.2.75.2) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2.75.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.2.75) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2.3.20) Spike RBD Protein; SARS-CoV-2 Omicron (B.1.1.529) S1+S2 trimer Protein...

The SARS-CoV-2 Alpha Spike Protein RBD refers to the receptor-binding domain (RBD) of the spike (S) protein found in the Alpha variant of the SARS-CoV-2 virus, which is responsible for COVID-19. The RBD is a crucial region within the S1 subunit of the spike protein that specifically binds to the angiotensin-converting enzyme 2 (ACE2) receptor on the surface of human cells, facilitating viral entry. The Alpha variant, first identified in the UK, has several mutations in the spike protein, including in the RBD, which can enhance the virus's ability to bind to ACE2, potentially increasing its transmissibility and impacting the effectiveness of immune responses. Understanding these mutations is vital for developing and adjusting vaccines and therapeutic strategies.
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Spezifikation

Antigen SARS-CoV-2 Alpha Spike Protein RBD Chimeric
Anwendungen ELISA, Neutralization
Klassifikation Recombinant Monoclonal
Klon D004
Konzentration 1 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with no preservative
Wirtsspezies Human
Immunogen Recombinant SARS-CoV-2 Alpha Spike ECD Protein.
Reinigungsverfahren Protein A
Menge 100 μg
Regulatorischer Status RUO
Primär oder sekundär Primary
Zielspezies Virus
Inhalt und Lagerung -20°C, Avoid Freeze/Thaw Cycles
Produkttyp Antibody
Form Liquid
Isotype IgG1 κ
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