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Invitrogen™ SARS-CoV-2 Spike Protein (RBD) (V367F) Fc Chimera Recombinant Protein

Artikelnummer. 17986241
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Menge:
100 μg
Packungsgröße:
100 Mikrogramm
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Artikelnummer. Menge Packungsgröße
17986241 100 μg 100 Mikrogramm
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Product Code. 17986241 Supplier Invitrogen™ Supplier No. RP88398
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    548.00 €
    531.56 € / 100 Mikrogramm
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Verfügbar ab: 15-12-2026
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Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (400 μL) be added to the vial to prepare a stock solution of 0.25 mg/mL. Concentration is measured by UV.

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.
TRUSTED_SUSTAINABILITY

Specifications

Zur Verwendung mit (Anwendung) Binding Assay, Control, ELISA Standard
Format Lyophilized
Zusammensetzung PBS with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
Molekulargewicht 51.54 kDa
Name SARS-CoV-2 Spike Protein (RBD) (V367F) Fc Chimera
pH-Bereich 7.4
Reinigungsverfahren Purified
Menge 100 μg
Lagerungsbedingungen -20°C, Avoid Freeze/Thaw Cycles
Regulatorischer Status RUO
Endotoxin-Konzentration <1.0 EU/μg
Gen-Alias Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Gebräuchliche Bezeichnung SARS-CoV-2 Spike Protein RBD
Biologische Aktivität The SARS-CoV-2 (2019-nCoV) Spike RBD-mFc (V367F) Recombinant Protein can bind with Human ACE2 in functional ELISA assay.
Produkttyp Protein
Konjugat Unconjugated
Rekombinant Recombinant
Proteinmarkierung Fc-tag
Sequenz SARS-CoV-2 spike RBD (Accession # YP_009724390.1), amino acids Arg319-Phe541 with a V367F substitution and a C-terminal mouse IgG1 Fc region
Inhalt und Lagerung -20°C, Avoid Freeze/Thaw Cycles
Aktivität The SARS-CoV-2 (2019-nCoV) Spike RBD-mFc (V367F) Recombinant Protein can bind with Human ACE2 in functional ELISA assay.
Expressionssystem HEK293 cells
Form Lyophilized
Reinheits- oder Qualitätsgrad >90% as determined by SDS-PAGE.
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