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Invitrogen™ SART1 Recombinant Rabbit Monoclonal Antibody (24GB4210)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA557243
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Beschreibung
SART1 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow
This gene encodes two proteins, the SART1protein expressed in the nucleus of the majority of proliferating cells, and the SART1protein expressed in the cytosol of epithelial cancers. The SART1protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.
Spezifikation
| SART1 | |
| Recombinant Monoclonal | |
| Unconjugated | |
| SART1 | |
| Ara1; Haf; Hom s 1; HOMS1; hSART-1; hSnu66; Hypoxia-associated factor; IgE autoantigen; MGC2038; mSART-1; rSART-1; Sart1; SART-1; SART1(259) protein; SART1(800) protein; SART1259; small nuclear ribonucleoprotein 110kDa (U4/U6.U5); SNRNP110; Snu66; SNU66 homolog; squamous cell carcinoma antigen recognised by T cells; squamous cell carcinoma antigen recognized by T cells; squamous cell carcinoma antigen recognized by T cells 1; squamous cell carcinoma antigen recognized by T-cells 1; U4/U6.U5 tri-snRNP-associated 110 kDa protein; U4/U6.U5 tri-snRNP-associated protein 1; U5-110K | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 20227, 29678, 9092 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 24GB4210 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O43290, Q5XIW8, Q9Z315 | |
| SART1 | |
| A synthesized peptide derived from human SNUT1 (aa 660-735). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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