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Invitrogen™ Siplizumab Recombinant Monoclonal Antibody
Beschreibung
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
Siplizumab has been shown to cause depletion of T-cells. It is therefore considered to be an immunomodulator in clinical settings where the depletion of T-cells may have clinical benefits, such as certain autoimmune diseases and T-cell cancers. In addition, preclinical studies have also suggested that siplizumab, by binding to the CD2 receptor, may selectively produce cell death and reduce cancerous cells.
Spezifikation
Spezifikation
| Antigen | Siplizumab Humanized |
| Anwendungen | ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance |
| Klassifikation | Recombinant Monoclonal |
| Konzentration | 1 mg/mL |
| Konjugat | Unconjugated |
| Zusammensetzung | 25 mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2 |
| Gen-Alias | MEDI-507 |
| Wirtsspezies | Human |
| Reinigungsverfahren | Protein A |
| Menge | 1 mg |
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