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  5. Tocris Bioscience™ SIS3

Tocris Bioscience™ SIS3
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Artikelnummer. 18772459
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Menge:
10 mg
50 mg
Packungsgröße:
10 Milligramm
50 Milligramm
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Artikelnummer. 18772459

Marke: Tocris Bioscience™ 5291/50

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Beschreibung

Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

SIS3 is a selective Smad3 inhibitor; attenuates TGF-β1-dependent Smad3 phosphorylation and DNA binding. Has no effect on Smad2, p38 MAPK, ERK or PI 3-kinase signaling. Inhibits TGF-β1-induced myofibroblast differentiation of dermal fibroblasts. Also inhibits TGF-β2-induced endothelial cell differentiation in iPSCs.
TRUSTED_SUSTAINABILITY

Spezifikation

Menge 50 mg
Produkttyp SIS3
Reinheit 97%
Molekulargewicht 489.99

Nur für Forschungszwecke

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