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Invitrogen™ Human SNF1LK2, GST Tag Recombinant Protein

Artikelnummer. 10064044
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Menge:
10 μg
100 μg
Unit Size:
1 Stück
100 Mikrogramm
Product Code. Menge unitSize
10064044 10 μg 1 Stück
15428673 100 μg 100 Mikrogramm
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Nur für Forschungszwecke. Die Anwendung muss den Produktanweisungen entsprechen.

Product Code. 10064044

Brand: Invitrogen™ PV4792

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This item is not returnable. View return policy

Nur für Forschungszwecke. Die Anwendung muss den Produktanweisungen entsprechen.

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

SNF1LK2 (QIK) is a serine/threonine kinase and is a salt-inducible kinase that belongs to the AMP-activated protein kinase family. SNF1LK2 negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1'alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing CREB-mediated gene expression after oxygen-glucose deprivation.
TRUSTED_SUSTAINABILITY

Specifications

Zugriffsnummer Q9H0K1
Konzentration See Label
Zur Verwendung mit (Anwendung) Kinase Assay
Zusammensetzung 50mM tris with 2mM DTT, 0.04% Triton X-100, 150mM NaCl, 0.5mM EDTA, 50% glycerol and no preservative; pH 7.5
Gen-ID (Entrez) 23235
Molekulargewicht 131.4 kDa
Name Human SNF1LK2, GST Tag
pH-Bereich 7.5
Reinigungsverfahren Purified
Menge 10 μg
Lagerungsbedingungen -80°C, Avoid Freeze/Thaw Cycles
Kennzeichnung RUO
Gen-Alias G630080D20Rik; KIAA0781; LOH11CR1I; QIK; Qin-induced kinase; RGD1559698; salt induceable kinase 2; salt inducible kinase 2; salt-inducible kinase 2; salt-inducible protein kinase 2; salt-inducible serine/threonine kinase 2; serine/threonine-protein kinase SIK2; Serine/threonine-protein kinase SNF1-like kinase 2; Sik2; SIK-2; SNF1-like kinase 2; SNF1LK2
Gebräuchliche Bezeichnung SIK2
Gensymbol SIK2
Kinase-Familie CAMKL Kinase Family
Produkttyp Protein
Konjugat Unconjugated
Spezies Human
Rekombinant Recombinant
Proteinmarkierung GST-tag
Sequenz Full length
Inhalt und Lagerung -80°C, Avoid Freeze/Thaw Cycles
Assay-Eingabe Biochemical binding/kinetic, Biochemical phospho-specific activity (no antibody)
Kinase-Gruppe Ser⁄Thr Kinases: CAMK Group
Versandbedingung Dry Ice
Systemkompatibilität Z'-LYTE™
Zieleintrag SNF1LK2
Zielgen SNF1-like kinase 2
Expressionssystem Insect cells
Proteinfamilie Kinases & Inhibitors
Proteinform Recombinant, Full Length
Form Liquid
Protein-Subtyp Serine/Threonine Kinases
Forschungskategorie Signal Transduction
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