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Invitrogen™ SOCS7 Recombinant Rabbit Monoclonal Antibody (24GB1820)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA557272
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Beschreibung
SOCS7 Recombinant Monoclonal Antibody for Western Blot, Flow
SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. SOCS7 may be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Spezifikation
| SOCS7 | |
| Recombinant Monoclonal | |
| 0.2 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O14512, Q8VHQ2 | |
| SOCS7 | |
| A synthesized peptide derived from human SOCS7 (aa 1-50). | |
| 20 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 24GB1820 | |
| Unconjugated | |
| SOCS7 | |
| 2310063P06Rik; C85125; Cish7; NAP4; NAP-4; Nck, Ash and phospholipase C binding protein; nck, Ash and phospholipase C gamma-binding protein; NCKAP4; Nck-associated protein 4; SH2 domain containing SOCS box protein SOCS7; SOCS6; SOCS7; SOCS-7; suppressor of cytokine signaling 6; suppressor of cytokine signaling 7 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 192157, 287659, 30837 | |
| -20°C | |
| Liquid |
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