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Invitrogen™ SOX2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marke: Invitrogen™ PA585143
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Beschreibung
Keep as concentrated solution. Predicted reactivity: Mouse (92%), Rat (92%), Zebrafish (87%), Japanese Medaka (87%), Xenopus laevis (85%), Cat (96%), Pig (97%), Chicken (93%), Sheep (97%), Rhesus Monkey (98%), Bovine (97%). Positive Control: NT2D1, A431, Human ESC, GL261. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.
Spezifikation
| SOX2 | |
| Polyclonal | |
| Unconjugated | |
| SOX2 | |
| ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 20674, 6657 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Flow Cytometry, Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| P48431, P48432 | |
| SOX2 | |
| Recombinant protein encompassing a sequence within the center region of human SOX2. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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