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Staurosporin, 99+ %, Thermo Scientific Chemicals

Product Code. p-7042530
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Menge:
1 mg
5 mg
10 mg
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1 Milligramm
10 Milligramm
5 Milligramm
This item is not returnable. View return policy

Product Code. 15495139

missing translation for 'mfr': Thermo Scientific Alfa Aesar J62837.M^

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Description

Staurosporin (CAS-Nr. 62996-74-1) ist ein bakterielles Alkyloid, das aus Streptomyces staurosporeus isoliert wird.

Broad spectrum protein kinase inhibitor Staurosporine is used as anti-fungal and anti-hypertensive, which results to study the anti-cancer treatment. It acts as a precursor to protein kinase inhibitor midostaurin. It is also used to induce cell death in Swiss Webster primary macrophage cells and to study the effect of caspase activation on human sperm quality.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Anwendungen
Der breit gefächerte Proteinkinase-Inhibitor Staurosporin wird als Antimykotikum und Antihypertensivum eingesetzt, was zur Untersuchung der Krebsbehandlung führt. Er dient als Vorläufer des Proteinkinase-Inhibitors Midostarin. Er wird auch verwendet, um den Zelltod in den primären Makrophagezellen von Swiss Webster zu induzieren und die Wirkung der Caspase-Aktivierung auf die Qualität menschlicher Spermien zu untersuchen.

Löslichkeit
Löslich in DMSO oder Ethanol. Löslich in Dimethylsulfoxid, Dimethylformamid, Ethylacetat, heißem Aceton und Ethanol. Schwer löslich in Chloroform und Methanol. Unlöslich in Wasser.

Hinweise
Kühl lagern. Nicht kompatibel mit starken Oxidationsmitteln.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 62996-74-1
Summenformel C28H26N4O3
Molekulargewicht (g/mol) 466.541
MDL-Nummer MFCD00077402
InChI-Schlüssel HKSZLNNOFSGOKW-ZYSRIHRCSA-N
Synonym Antibiotic AM-2282
PubChem CID 49831000
SMILES CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC

Specifications

Chemischer Name oder Material Staurosporine
Typ Staurosporine
Physikalische Form Pulver
Schmelzpunkt 240°bis 243 °C
Farbe Gelb
Menge 1 mg
Beilstein 1060573
Merck Index 14,8802
Löslichkeitsinformationen Soluble in DMSO or ethanol;Soluble in dimethyl sulfoxide ,dimethyl formamide,ethyl acetate,hot acetone and ethanol; Slightly soluble in chloroform and methanol; Insoluble in water.
Formelmasse 466.54
Reinheit (%) ≥99%
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Safety and Handling

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Product Identifier
  • Staurosporine
 Signal Word
  • Achtung
 Hazard Category
  • Karzinogenität Kategorie 2
 Hazard Statement
  • H351-Kann vermutlich Krebs erzeugen.
 Precautionary Statement
  • P201-Vor Gebrauch besondere Anweisungen einholen.
  • P280-Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.
  • P308+P313-BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
SDS

RUO – Research Use Only

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