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Invitrogen™ TAF1C Recombinant Rabbit Monoclonal Antibody (3O8T1)
Beschreibung
Immunogen sequence: PWDPGLTARD LLFRGGCRYR KRPRVVLDVT EQISRFLLDH GDVAFAPLGK LMLENFKLEG AGSRTKKKTV VSVKKLLQDL GGHQPWGCPW AYLSNRQRRF SILGGPILGT SVASHLAELL HEELVLRWEQ LLLDEACTGG ALAWVPG.
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF. Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
Spezifikation
Spezifikation
| Antigen | TAF1C |
| Anwendungen | ELISA, Western Blot |
| Klassifikation | Recombinant Monoclonal |
| Klon | 3O8T1 |
| Konzentration | 1.04 mg/mL |
| Konjugat | Unconjugated |
| Zusammensetzung | PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3 |
| Gen | TAF1C |
| Gen-Zugriffsnummer | Q15572, Q6P773 |
| Gen-Alias | MGC:39976; mTAFI95; RNA polymerase I-specific TBP-associated factor 110 kDa; RNA polymerase I-specific TBP-associated factor 95 kDa; SL1; SL1, 110kD subunit; TAF1C; TAFI110; TAFI95; TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C; transcription factor TAFI95; TATA box binding protein associated factor 1C; TATA box-binding protein-associated factor 1C; TATA box-binding protein-associated factor RNA polymerase I subunit C; TATA box-binding protein-associated factor, RNA polymerase I, subunit C; TATA-box binding protein associated factor, RNA polymerase I subunit C; TATA-box binding protein associated factor, RNA polymerase I, C; TBP-associated factor 1C; TBP-associated factor RNA polymerase I 95 kDa; transcription factor SL1; transcription factor TAFI95; transcription initiation factor SL1/TIF-IB subunit C |
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