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Tetraethylmethylendiphosphonat, 98+%, Thermo Scientific Chemicals
Beschreibung
Tetraethyl methylidenediphosphonate is used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters. It acts as an intermediate for the synthesis of bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity. It is also used as a reactant for synthesis of dual substrate-site inhibitors of 3-deoxy-D-arabino-heputosonate 7-phosphate synthase and alpha-amino acid derivatives containing gem-biophosphonates, Lycopene through Wittig-Horner reaction. It is also used as a precursor for the preparation of dendritic polyglycerol anions.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Methandiphosphonsäuretetraethylester wird bei der Synthese von Tetrazolochinolin-basierten Mono- und Bisphosphonatestern verwendet. Es dient als Zwischenprodukt für die Synthese von Bisphosphonat- und Bisphosphonsäure-Derivaten mit antikarzinogener und antischistosomaler Aktivität. Es wird auch als Reaktant für die Synthese von doppelten Substratstellen-Inhibitoren von 3-deoxy-D-arabino-heputosonat7-phosphat-Synthase und alpha-Aminosäure-Derivaten verwendet, die gem-Bisphosphonate, Lykopen durch Wittig-Horner-Reaktion enthalten. Es wird auch als Vorläufer für die Herstellung von dendritischen Polyglycerolanionen verwendet.
Löslichkeit
Leicht mit Wasser mischbar.
Hinweise
Nicht kompatibel mit starken Oxidationsmitteln.
Specifications
Specifications
| Chemischer Name oder Material | Tetraethyl methylenediphosphonate |
| Dichte | 1.162 |
| Siedepunkt | 151°C to 153°C (1.2 mmHg) |
| Flammpunkt | >110°C (230°F) |
| Brechungsindex | 1.44 |
| Menge | 100 g |
| Beilstein | 1813241 |
| Löslichkeitsinformationen | Slightly miscible with water. |
| IUPAC-Name | 1-[Diethoxyphosphorylmethyl(ethoxy)phosphoryl]oxyethan |
| Formelmasse | 288.22 |
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RUO – Research Use Only
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