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Invitrogen™ TGF beta-1,2,3 Monoclonal Antibody (1D11)
Mouse Monoclonal Antibody
Marke: Invitrogen™ MA523795
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Beschreibung
This antibody recognizes human TGF-beta 1, TGF-beta 2, and TGF-beta 3. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method. Neutralization: measured by its ability to neutralize TGF beta-1 inhibition of IL-4-dependent proliferation in the HT-2 mouse T cell line. The Neutralization Dose (ND50) is typically 0.25-1.25 μg/mL in the presence of 1 ng/mL Recombinant Human TGF beta-1 and 7.5 ng/mL Recombinant Mouse IL-4.
TGF-beta1, -2, and -3 are a closely related group of proteins (70-80% sequence homology) that are produced by many cell types and function as growth and differentiation factors. The active forms of TGF-beta1, -2, and -3 are disulfide-linked homodimers.
Spezifikation
| TGF beta-1,2,3 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 5% trehalose and No Preservative | |
| P01137, P04202, P09531, P10600, P16047, P17125, P18341, P21214, P27090, P30371, P61812 | |
| TGFB1, TGFB2, TGFB3 | |
| Bovine bone-derived TGF-beta 1 and TGF-beta 2. | |
| 500 μg | |
| Primary | |
| Human, Mouse, Bovine, Chicken | |
| Antibody | |
| IgG1 |
| ELISA, Inhibition Assays, Neutralization, Western Blot | |
| 1D11 | |
| Unconjugated | |
| TGFB1 | |
| CED; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; tgf beta 1; tgf beta 3; tgf beta1; TGFB; Tgfb1; Tgfb-1; TGFB4; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; TGF-beta4; tissue growth factor-beta4; Transforming growth factor; transforming growth factor beta 1; transforming growth factor beta 4; transforming growth factor beta 4 precursor; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta-1 precursor | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 100873157, 21803, 21808, 21809, 282089, 396438, 421352, 534069, 538957, 7040, 7042, 7043 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
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