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Invitrogen™ Human TGFBR1 (ALK5), GST Tag Recombinant Protein

Artikelnummer. 15428713
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Menge:
1 mg
10 μg
100 μg
Packungsgröße:
1 Milligramm
1 Stück
100 Mikrogramm
Artikelnummer. Menge unitSize
15428713 100 μg 100 Mikrogramm
10479684 10 μg 1 Stück
15468793 1 mg 1 Milligramm
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Artikelnummer. 15428713

Marke: Invitrogen™ PR9075A

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Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1. TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).
TRUSTED_SUSTAINABILITY

Specifications

Zugriffsnummer P36897
Konzentration See Label
Zur Verwendung mit (Anwendung) Kinase Assay
Zusammensetzung 50mM tris with no preservative
Gen-ID (Entrez) 7046
Molekulargewicht 62.9 kDa
Name Human TGFBR1 (ALK5), GST Tag
Reinigungsverfahren Purified
Menge 100 μg
Lagerungsbedingungen -80°C, Avoid Freeze/Thaw Cycles
Kennzeichnung RUO
Gen-Alias AAT5; activin A receptor type II-like kinase, 53kDa; activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ACVRLK4; ALK5; Alk-5; AU017191; ESK2; ESS1; LDS1; LDS1A; LDS2A; MSSE; mutant transforming growth factor beta receptor I; ser; serine/threonine-protein kinase receptor R4; SKR4; TbetaRI; tbetaR-I; tgf beta receptor 1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; TGFBR1; TGFR1; TGFR-1; Transfor; transforming growth factor beta receptor 1; transforming growth factor beta receptor I; transforming growth factor, beta receptor 1; transforming growth factor, beta receptor I; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa); transforming growth factor-beta receptor type I
Gebräuchliche Bezeichnung TGFBR1
Gensymbol TGFBR1
Kinase-Familie STKR Kinase Family
Proteinlänge 1-503
Produkttyp Protein
Konjugat Unconjugated
Spezies Human
Rekombinant Recombinant
Proteinmarkierung GST-tag
Sequenz 1-503
Inhalt und Lagerung -80°C, Avoid Freeze/Thaw Cycles
Kinase-Gruppe Ser⁄Thr Kinases: TKL Group
Versandbedingung Dry Ice
Expressionssystem Baculovirus
Proteinfamilie Kinases & Inhibitors
Proteinform Recombinant, Full Length
Form Liquid
Protein-Subtyp Serine/Threonine Kinases
Forschungskategorie Signal Transduction
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