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Invitrogen™ TIM-6 Polyclonal Antibody

Goat Polyclonal Antibody
Marke: Invitrogen™ PA5148623
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Beschreibung
Reconstitute at 0.2 mg/mL in sterile PBS.
TIM-6, or T-cell immunoglobulin and mucin-domain containing-6, is a member of the TIM gene family, which plays a significant role in the regulation of immune responses. The TIM family proteins are type I membrane glycoproteins primarily expressed on the surface of various immune cells, including T cells, B cells, and dendritic cells. Although TIM-6 is less well-characterized compared to other members of the TIM family, such as TIM-1, TIM-3, and TIM-4, it is believed to be involved in modulating immune cell interactions and signaling pathways. TIM proteins are known to participate in processes such as T cell activation, tolerance, and the clearance of apoptotic cells. Dysregulation of TIM family proteins has been associated with autoimmune diseases, allergic responses, and cancer, suggesting that TIM-6 may also play a role in these conditions. Understanding the specific functions and mechanisms of TIM-6 within the immune system is crucial for developing potential therapeutic strategies aimed at modulating immune responses in various diseases. Research into TIM-6 can provide valuable insights into the broader roles of the TIM family in immune regulation and their potential as targets for immunotherapy.
Spezifikation
| TIM-6 | |
| Polyclonal | |
| Unconjugated | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| Mouse | |
| Antibody | |
| IgG |
| Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| Mouse myeloma cell line NS0-derived recombinant mouse TIM-6, Glu24-Ala140. | |
| 100 μg | |
| Primary | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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