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Invitrogen™ TIMP4 Polyclonal Antibody
Goat Polyclonal Antibody
Marke: Invitrogen™ PA5149497
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Beschreibung
Reconstitute at 0.2 mg/mL in sterile PBS.
Tissue inhibitor of metalloproteinase 4 (TIMP4) is encoded by the gene TIMP4 located on chromosome 3. It belongs to the family of TIMP genes and is known to inhibit the activity of matrix metalloproteinases. Matrix metalloproteinases (MMP) are a group of proteinases that degrade the components of extracellular matrix. TIMP4 irreversibly binds to MMPs and inactivates them with the help of zinc as a cofactor. The netrin domain of TIMP4 is involved in platelet recruitment and aggregation. Other biological functions include response to cytokine and peptide hormone stimuli and involvement with the ovulation cycle and CNS development.
Spezifikation
| TIMP4 | |
| Polyclonal | |
| Unconjugated | |
| TIMP4 | |
| Metalloproteinase inhibitor 4; TIMP 4; TIMP metallopeptidase inhibitor 4; TIMP4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4 | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 110595, 7079 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| ELISA, Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| Q99727, Q9JHB3 | |
| TIMP4 | |
| Mouse myeloma cell line NS0-derived recombinant human TIMP-4, Cys30-Pro224. | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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